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J Am Soc Nephrol ; 2021 Feb 18.
Article in English | MEDLINE | ID: covidwho-1496680

ABSTRACT

Obesity is a leading public health problem that currently affects over 650 million individuals worldwide. Although interest in the adverse effects of obesity has grown exponentially in recent years, less attention has been given to studying its management in individuals with CKD. This relatively unexplored area should be considered a high priority because of the rapid growth and high prevalence of obesity in the CKD population, its broad impact on health and outcomes, and its modifiable nature. This article begins to lay the groundwork in this field by providing a comprehensive overview that critically evaluates the available evidence related to obesity and kidney disease, identifies important gaps in our knowledge base, and integrates recent insights in the pathophysiology of obesity to help provide a way forward in establishing guidelines as a basis for managing obesity in CKD. Finally, the article includes a kidney-centric algorithm for management of obesity that can be used in clinical practice.

3.
Lancet Diabetes Endocrinol ; 8(7): 640-648, 2020 07.
Article in English | MEDLINE | ID: covidwho-197827

ABSTRACT

The coronavirus disease 2019 pandemic is wreaking havoc on society, especially health-care systems, including disrupting bariatric and metabolic surgery. The current limitations on accessibility to non-urgent care undermine postoperative monitoring of patients who have undergone such operations. Furthermore, like most elective surgery, new bariatric and metabolic procedures are being postponed worldwide during the pandemic. When the outbreak abates, a backlog of people seeking these operations will exist. Hence, surgical candidates face prolonged delays of beneficial treatment. Because of the progressive nature of obesity and diabetes, delaying surgery increases risks for morbidity and mortality, thus requiring strategies to mitigate harm. The risk of harm, however, varies among patients, depending on the type and severity of their comorbidities. A triaging strategy is therefore needed. The traditional weight-centric patient-selection criteria do not favour cases based on actual clinical needs. In this Personal View, experts from the Diabetes Surgery Summit consensus conference series provide guidance for the management of patients while surgery is delayed and for postoperative surveillance. We also offer a strategy to prioritise bariatric and metabolic surgery candidates on the basis of the diseases that are most likely to be ameliorated postoperatively. Although our system will be particularly germane in the immediate future, it also provides a framework for long-term clinically meaningful prioritisation.


Subject(s)
Bariatric Surgery/methods , Betacoronavirus , Coronavirus Infections/surgery , Obesity/surgery , Pandemics , Pneumonia, Viral/surgery , Postoperative Care/methods , Bariatric Surgery/trends , COVID-19 , Coronavirus Infections/epidemiology , Disease Management , Humans , Obesity/epidemiology , Pneumonia, Viral/epidemiology , Postoperative Care/trends , Postoperative Complications/epidemiology , Postoperative Complications/prevention & control , SARS-CoV-2
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